Cheap Flights from Madrid to Santiago

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Flight deals from Madrid to Santiago

Looking for a cheap last-minute deal or the best return flight from Madrid to Santiago? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Madrid to Santiago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Madrid to Santiago flights are currently cheapest in September.

Direct flights from Madrid to Santiago

Madrid to Santiago: Alternative routes

Compare routes from Madrid to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

Madrid to Santiago: Flight information

The things to know before you go.
Cheapest flight foundج.م.‏ 20,105
Cheapest month to flySeptember
Average flight time9 hrs, 6 mins
Most popular airlineCubana
Average flights per week4

Finding cheap flights from Madrid to Santiago: Frequently asked questions

The best price we found for a return flight from Madrid to Santiago is ج.م.‏ 57,573. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
9 hours and 6 minutes is the average flight time from Madrid to Santiago.
Cubana and Plus Ultra Lineas Aereas fly direct from Madrid to Santiago.
As of September 2025, there are 4 flights per week flying from Madrid to Santiago.
The cheapest month to fly from Madrid to Santiago is usually January.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Madrid Airport to Santiago Airport on Friday, 9 January 2026.
Yes – the average flight time is 9 hours and 6 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santiago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, American Airlines offers the cheapest flight tickets to Santiago.

Travelling from Adolfo Suarez Madrid-Barajas Airport (MAD) to Antonio Maceo Airport (SCU): what you need to know

  • Book a direct flight from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport and you'll be in the air for an average of 9 hours 25 minutes.

  • Santiago's timezone is UTC-4, which makes Santiago five hours behind Madrid.

  • Give yourself plenty of time to make your MAD to SCU flight. Generally, it's best to arrive two hours before international departures and an hour ahead for domestic flights.

  • During popular months like July, it's a good idea to get to the airport earlier. Plan to arrive two hours before domestic departures and four hours ahead for international flights when you fly during a peak period in general.

  • Cubana de Aviacion offers direct flights from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport. Book with this popular airline, then get ready to discover the sights in Santiago — and maybe even more of Cuba if your schedule allows.

  • The airline most travellers fly with on this route is Cubana de Aviacion.

  • Pick a stopover if you'd like to break up your flight. Simply uncheck 'Direct flights only' to look at all your options for tickets from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport. Miami International Airport is a top stopover on the MAD to SCU route.

How to find the cheapest flights from Adolfo Suarez Madrid-Barajas Airport (MAD) to Antonio Maceo Airport (SCU)

  • At the moment, ج.م.‏ 20,105 is the cheapest price we've seen for a one-way Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport flight. The best price for a return plane ticket is ج.م.‏ 57,466. Remember that fares can change due to demand when booking.

  • Don't wait until the last minute. You're more likely to find cheap tickets from MAD to SCU if you book ahead. Airlines often have some excellent early bird rates.

  • Organise your trip for November. That's the cheapest month for flights from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport. If your travel dates are flexible, use the 'Whole month' tool to see the lowest airfare across every month.

  • Landing cheap flights from MAD to SCU is a breeze with Price Alerts. Simply create one of these automatic alerts and we'll let you know when a new discounted fare appears.

  • Tailor your flights using filters. Select your preferred departure and arrival times, airlines and total journey duration. You can also sort results by 'Cheapest,' 'Best' or 'Fastest' flights from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport.

Handy information about Adolfo Suarez Madrid-Barajas Airport (MAD)

  • Of the departures from Adolfo Suarez Madrid-Barajas Airport, 78.23% arrive as scheduled at their destination.

  • Central Madrid to Adolfo Suarez Madrid-Barajas Airport is around 18 kilometres. Depending on traffic, it'll take you about 25 minutes to get there if you're driving, catching a cab or ride-sharing.

  • Expect a journey time of around 35 minutes on public transport.

  • Have an early flight from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport? Avoid the last-minute rush to the airport (and enjoy a little extra shut-eye) by choosing one of these stays near MAD:

Arriving at Antonio Maceo Airport (SCU)

Getting from Antonio Maceo Airport (SCU) to central Santiago

  • Antonio Maceo Airport to the centre of Santiago has a drive time of around 10 minutes. It's approximately 6 kilometres away.

When to fly to Antonio Maceo Airport (SCU)

  • The quietest month for a flight from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport is April, while July is the most popular. Choose the ideal time to visit Santiago based on whether you prefer a bustling atmosphere or a more laid-back vibe.

  • The warmest month in Santiago is August, with the temperature ranging between 23ºC and 34ºC. Lock in your flights from Adolfo Suarez Madrid-Barajas Airport to Antonio Maceo Airport in this month if this is the kind of weather you like.

  • Search for cheap tickets from MAD to SCU in January if you like cooler conditions. Temperatures are at their lowest then, ranging between 18ºC and 30ºC on average.

Explore more of Cuba

  • Santiago has plenty going for it, but there are so many other parts of Cuba just waiting to be discovered. Around 257 kilometres north-west of Santiago, a visit to Camaguey will keep you on the move. Start with popular sights like Iglesia de Nuestra Senora de la Merced, Plaza del Carmen and Museo Casa Natal de Carlos J. Finlay.

  • If you're interested in discovering another major destination in Cuba, head for Holguin, about 105 kilometres north-west of Santiago. El Chorro de Maita Museum, Bahia de Naranjo Nature Park and La Loma De La Cruz are key reasons to visit.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.