Cheap Flights from Santo Domingo to Medellin

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Flight deals from Santo Domingo to Medellin

Looking for a cheap last-minute deal or the best return flight from Santo Domingo to Medellin? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Santo Domingo to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santo Domingo to Medellin flights are currently cheapest in May.

Direct flights from Santo Domingo to Medellin

Alternative Santo Domingo to Medellin routes

Looking for the cheapest, fastest or easiest route from Santo Domingo to Medellin? You could fly into the following airports instead.

Santo Domingo to Medellin: Flight information

The things to know before you go.
Cheapest flight foundج.م.‏ 5,089
Cheapest month to flyMay
Average flight time2 hrs, 33 mins
Most popular airlineArajet
Average flights per week22

Finding cheap flights from Santo Domingo to Medellin: Frequently asked questions

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.
The best price we found for a return flight from Santo Domingo to Medellin is ج.م.‏ 10,792. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 33 minutes is the average flight time from Santo Domingo to Medellin.
Arajet, TAMPA Cargo and World Ticket Ltd fly direct from Santo Domingo to Medellin.
As of May 2025, there are 22 flights per week flying from Santo Domingo to Medellin.
The cheapest month to fly from Santo Domingo to Medellin is usually May 2025.
If you're flying from Santo Domingo, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 18.9 km away from the centre of Medellin. We've found flights into this airport from ج.م.‏ 10,792.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santo Domingo to Medellin on Saturday, 31 May 2025.
Yes – the average flight time is 2 hours and 33 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 18°C. May is typically the warmest month in Medellin, when it usually averages around 21°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 15°C. The rainiest month is May.
The cheapest airline that flies to Medellin is Arajet .

Travelling from Santo Domingo to Medellin: what you need to know

  • There are two main airports you can fly out of in Santo Domingo. Explore your options leaving from Las Americas International Airport (SDQ) or Dr. Joaquin Balaguer International Airport (JBQ) when reserving your flight from Santo Domingo to Medellin.

  • Hop off the plane at Jose Maria Cordova International Airport (MDE), the primary gateway of Medellin.

  • Around 2 hours 35 minutes is how long you'll be in transit on a direct Santo Domingo to Medellin flight.

  • The timezone in Medellin is UTC-5, which is one hour behind Santo Domingo.

  • Las Americas International Airport (SDQ) to Jose Maria Cordova International Airport (MDE) is the most traveled route between these two cities. There are nine flights a week to pick from. If you have things to finalize before heading off, the last flight from Santo Domingo to Medellin is with Wingo at 21:28. Opt for the first SDQ to MDE departure with Arajet at 06:00 to make the most of your first day in Medellin.

  • Leave plenty of time to catch your Santo Domingo to Medellin flight. A good rule of thumb is to arrive two hours before international departures and an hour ahead for domestic flights.

  • Be prepared for longer lines in popular months like January. Arriving up to four hours in advance for an international flight and two hours for domestic departures is a smart move.

How to find the cheapest flights from Santo Domingo to Medellin

  • Score cheap Santo Domingo to Medellin flights by booking two months ahead. Based on our research, that's the ideal time for finding the biggest deals.

  • The best month for landing cheap plane tickets from Santo Domingo to Medellin is May. Use the 'Whole month' tool to compare prices, then choose the dates that offer the biggest savings.

  • Spend less time searching for cheap flights from Santo Domingo to Medellin by setting up a Price Alert. You'll receive an email or notification through the app when a lower fare pops up.

  • Choose your preferred departure and arrival times, number of stops and airlines by using the filters. Or sort your Santo Domingo to Medellin flight results by 'Fastest,' 'Best' or 'Cheapest.'

Flying from Santo Domingo

Las Americas International Airport (SDQ)

  • You can book a direct flight from Santo Domingo to Medellin jetting off from Las Americas International Airport (SDQ). Start your trip at SDQ and end it at Jose Maria Cordova International Airport (MDE).

  • Arajet is a leading airline that offers direct Santo Domingo to Medellin plane tickets from SDQ.

  • Think about adding a stopover to possibly find a cheaper Santo Domingo to Medellin flight. Simply uncheck 'Direct flights only' when searching for departures from Las Americas International Airport. Break up your trip (and maybe save some cash) by stopping at one of these popular airports:

    • El Dorado International Airport (BOG)

    • Rafael Nunez International Airport (CTG)

    • Simon Bolivar International Airport (CCS)

  • SDQ is around 27 kilometres from central Santo Domingo. If you're ride-sharing, catching a cab or driving from the centre, it'll take you 30 minutes or so to arrive, depending on the traffic.

  • In search of a handy hotel close to Las Americas International Airport? If you're boarding an early flight from Santo Domingo to Medellin, these stays will put you nice and close to your departure gate:

  • 72.45% of flights that leave from Las Americas International Airport make it to their destination on schedule.

Arriving in Medellin

Jose Maria Cordova International Airport (MDE)

Enrique Olaya Herrera Airport (EOH)

  • Central Medellin is approximately 3 kilometres from Enrique Olaya Herrera Airport (EOH). Once your flight from Santo Domingo to Medellin has touched down and you've made your way through the terminal, expect a drive of around 15 minutes.

  • You can expect the journey to take approximately 30 minutes on public transport.

  • Land, collect your Enrique Olaya Herrera Airport rental car, and drive off without skipping a beat. Confort Rent a Car and Green Motion are leading providers to select from here.

  • Avoid paying extra. Reserving your ride one week ahead of your arrival at EOH can land you a better rate.

Best time to go to Medellin

  • It's time to work out your trip dates for your flight from Santo Domingo to Medellin. August is the most popular month to visit Medellin. If you want a quieter atmosphere, go in April.

  • The warmest month in Medellin is August, with temperatures ranging between 11ºC and 27ºC. Lock in your Santo Domingo to Medellin ticket then if that's your definition of good weather.

  • If you like travelling in cooler conditions, look for a cheap flight from Santo Domingo to Medellin in July when temperatures average between 11ºC and 27ºC.

More about Medellin

  • After booking your flight from Santo Domingo to Medellin, find a hotel that offers the right mix of comfort and location. Make one of these options your base for exploring Medellin:

  • All great adventures should include some sightseeing. Parque Arvi, Comuna 13 and Botero Plaza are must-visits when exploring Medellin.

Explore more of Colombia

  • Medellin will leave a lasting impression, but there are so many other corners of Colombia you'll want to see. Around 241 kilometres south-east of Medellin, a trip to Bogota will keep you on the go. Start with attractions like Gold Museum, Usaquen Train Station and Urbanización Villas del Madrigal - Molino del Viento Park.

  • If you're looking to explore another major stop in Colombia, head for Cali, roughly 322 kilometres south of Medellin. Cristo Rey, Gato de Tejada and Caliwood Museo de la Cinematografia are the start of reasons to visit.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.